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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b5ba9a46f6c307ae12bf45f782e5080b472af01ca46f9d43d53dfc67298dc58' 
  AND token = 'REfvEtPygC1dFgiXAFTaGw+ocbVBJEBEbbXZRQuB0Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}