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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec59a32afcd50af61ae054ad8bf5ae2e5c1d7e608b1d815cee6b33aa48ba3410' 
  AND token = 'wi96bj++Unm58x+CdWChMhXueJdNzZvBETDZwfQneLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}