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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e5db6c9b020244b8310bddc9c600d92239c2dde0e743d47a24b3809daea7f96' 
  AND token = 'lMB1Ki8U1CnDETocKDQHDPFraQEgH9774Tq//jVtrdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}