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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c3b5c05135935d73b5646e52aded45908d17667860061a2f4e3550e527b047a' 
  AND token = 'XVJkv3XrqNZORbS1SwivLQ3ZH2b4hk2z4o9qfWFzTik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}