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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff581b70d06f8cf34f8f062718ebc4a7a1fd1e9bb9dda9d3fcccfa18670f80c5' 
  AND token = 'QSJuSf0vwsS+Uzok6Mz+Ab+eHoYhKTo4qCrPbiH9b4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}