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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be83c007099539a3b721a245e7ee05c3d059a77b5f29cfe44dd8b533ca5ade83' 
  AND token = 'vCPZtQqS54hmYxUNZdx5OaaIYDyw/YQAoRFmwYTzk8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}