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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36722108a13c900b6e0c850f9f8148eb97f929f07c1e4d46b6e756775dbd9cdc' 
  AND token = 'd78plwRyVMjNtgcb//Siyw/lFLDWpaW2Z9pp9JdQ3I8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}