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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3605c0b02e20c9970c217103155a892261101db3ddeaf1eb40b81c708780a0' 
  AND token = '7Y5UR+Z0z8tdXRWqO3Vf6bqCaeQh7CEdHwHMGhbcGSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}