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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c3e58cddaa500b91b32bd2543445cb22a87eeff85eb86fbd4bed1ae4511fc41' 
  AND token = 'fj9svcHVvGMwWs8UTn8Lk7KmrOoSB6+5NZJFySZ79N8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}