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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ce89c7d94a89e9e82b9875c6c3d3ea5b09de0ec9758c33e6b6757597a4ceff2' 
  AND token = 'GwqlAxUR2NrYs3Dni5yEij1TVOY3taCzX7SIY1eUx7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}