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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46fd9da0d40e567aa1e0e3e235b4a79ebb6dac9e8729e87fbb9417d44dd214d0' 
  AND token = 'T9BRAwQogW+uI4tx+C93xiySQDxBRQ2E9EZM8eLky50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}