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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5726d5d31f1e989fedf415c67c045195802f8f186a7354c68a5b5df77bfa39d' 
  AND token = 'dhLTSRAC25IlAIWaMIdTSR0JX5yNmYGthjyASmhLQ3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}