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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b604e85a125b3f8b840a105acd3acf32aa2ddb0ea1c55a8d6417a637e820a7e8' 
  AND token = '6zv0N2T9XmhudYxh/xt4QYkP05nP0boUyqkdSMsj75c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}