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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b424a146f21984c3d040030ae51fdfaceea1eb585a4c53415428e1d564910dfd' 
  AND token = 'RJ7rQK0084ck/LqZO/3nslCg4N+v7s493Ddp0HPfHXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}