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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e6ecaf8bd98cad5da141020f8f0f788ac287a1756b9d96a9cded2ace72781f9' 
  AND token = 'ZX8PxuxUbam+VnMgBMc9lmzahD1XZ9w1SEMuI9ogR3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}