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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c270ee3db8ffddab0030cd307cac0d4cb8a30354e6b6d5ba4ec7250c76613846' 
  AND token = 'nFHt/QVcBt/qherYF9IegO/9t0mzT/v8hXUOz+Cu12I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}