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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b86d90e8a6c5c2901d19aeba36fdadf6ada3f744d3decd57a5297cd1a9b5b0' 
  AND token = 'At9cEYS5tqka5zLko2R5BoRfMZuzaN9BNu8YKPxT7xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}