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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0eeaa6c1bebba3d6fd58866744f0dc6743e2e2ae607047a89996be516d47174' 
  AND token = 'z2c3gsadu8wO0+rHcZlY2B/UvWZBdPdHVAW7foMaHQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}