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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149223e9df4092269c52ce6688747a5dfe1ce6c6118f32e5b4ae4a03c11e430b' 
  AND token = 'QETcz5zWOw4s111G53AsTcpGDoGDuMP8JTjm9t//wCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}