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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b01efe6c715c52f4efdb605c21c5640f53c0ff63fcf02d9136b105fb29593629' 
  AND token = 'ywxAWJ3ioFCTMGrgVlSdADsjgN9wD6Uy9mMNxBn27S4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}