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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ad8698b82d3cb835166b6203d167dd559dc8f2a36e5c2ab02e2144a6fd9d853' 
  AND token = 'lEVoHt/rOwdkVWXI2pb/iu+ZHS8EkjwNOej4FhEm3B0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}