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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08a80339e95e75b8b39c1d2cea8faf24f08c63e95e63ae5b75f2f1854c878e9a' 
  AND token = 'HVVmUyBm2/EP5PVgR1grRH43b2VRqRgzFuXR5Nf0nC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}