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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ae0aa5d58e67a6dbc47131f251826594afde85a86dd3cb1496f533fb31e8815' 
  AND token = 'zEUXFMfG81/nfsMXFRvl776NBbaHDm1X+A74FZ9VfJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}