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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aed1357bad9bfd5c283c739c3cdbfb5bb5a5b7baebdda54aa2887b119207409' 
  AND token = 'W9KO8XRdodz0TNsGX7lEGDRAZJFkWDUynu1qzzqL8FM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}