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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8f7963f86457d68d0ab12c5cf9ebadb6f22c40d635e0a68e4731a5b13fea534' 
  AND token = 'LpTHR657/OOTB+abV5b1RG2HGHBmlJrNikmgwFfhiVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}