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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c72ddf52c980c0eb476ef36d36dd79fa24c6e461aa3d061c2fed22030d4dd7d' 
  AND token = 'i1Bgabv02eTGQf2ZiZIgNoFOkSQ58xCKnfjIiB3We+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}