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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5c78b6328a289f692522338c5d0f55890ecd81aed1df3b23d4a2c9293d97887' 
  AND token = 'l4QvMCnwW+ZX1t8glhjk8oo+xdMiAjxgpER5SAQwY/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}