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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64cad74ded29438336374ba03cb4363679387b02a590fcf23e604ddda6ceb87f' 
  AND token = 'LQia1nkNtqjX3KQj1GQ8WnfUWS8JSdWkz5yI/UCKgzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}