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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06d46e274dd18763930862f4a85216d2c3b02b10737e58b8f6806a6166f7631e' 
  AND token = 'sqf4Rjg/m+ZJcdNgRcyDIK32UFakl/VLZUg1wR1UoS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}