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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51de0950508deb0b275b40e1f6bb1e2f91dd3ea48df339271025ccc81b5e885d' 
  AND token = 'qV6giOWWbpLlPtwul1GupaNJfHifFGF2dfOPB18cOn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}