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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfc24e0cf44a3699b7366db89e2ce14d8bb4c6267c9e1b8b88175e6bd22b1df0' 
  AND token = 'CQ6XVilFXuBUcCP13sUWHotG4dNQwlBDZhaf2rhJW50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}