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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6cb3df827dd0bc956e5c01921ee638964f4c9ea67a909c7462713bbd9a165e3' 
  AND token = '4InJ4L7Km7QBjreaVMe1xevLeprW490RGzi6rPrz2j8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}