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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '134461731e1aa40a1f32f16bcd638953057b66f44c26a30cd9af033915aa5d0f' 
  AND token = 'LK3IiSuuu0ibb3Mn+iKjNNE+I3NO6x08ujxJpYOWHHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}