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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed00615f4fa2233f3a09b99bdbe934a31ff2b2ee1f3973458df70df65fddd1c' 
  AND token = '8NQk41UON1jGQf80DOGBqxXnNeCG28SJX3R+G/8TumM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}