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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbc37afd597849c01c09a442eb38e9a4f3aed44d423cc79ac913003c9ab0ba68' 
  AND token = 'wtq8JvTr2JCWeguAdTlp1CHFcMV0DNTn6JAmUhEH2D8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}