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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d6959638659668bea0eef536481c717ac0e1d28419206443f4103593074204a' 
  AND token = 'fek3u62vRHKH9GrvqIj1E0HJOpVtrLIuN9/bL72KPHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}