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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a86775cc1ca50d0153f13aabf4dda84bdcf3527a289f496b9d8a91058764df8b' 
  AND token = 'ipryBKFPkqel+Dea4uqgFiBI0xFQ837lH3vRL3HDZR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}