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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f0272bf7148be1e9df2a8f9c7937496098d1761594b915f9f3718d7cccf0523' 
  AND token = 'ARBVOHb4OvV7GL6sbDpORQ97XlJ7f8y0u1uxmXIeOwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}