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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ed226d22e5c187d34c82030f837dd25bda9d942ad09340915bdeb739b5bccce' 
  AND token = 'W80+5ZWXGVZLrxbDCn+jHmfdXzH9AjOIneRPyozo/cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}