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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c72a10045e6a849624509ce39b6fd2a8ba320e626092e4379779cfe2456efbb1' 
  AND token = 'TLwB8EdM2NhfCIaSEs1EaDtSLyE70lYT+X3o1p5vBnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}