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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2166e43c7d4c9ac60a516f5c09b5b10e134d2ce4307a135b519308da09ea2371' 
  AND token = 'nPi40k5TDVp0V9Qmt/sSkJXIAbn1itzV0JLuk0ITGJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}