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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5b438b1b2c993d709aaf22d546a0faea72bff51cab73a8b39ce07d3b1279120' 
  AND token = 'm9Cnqi6kxC/Kkc1sMjwocYr9+6Dv15mGMBcURKseOZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}