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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9be7c2a8a9237c0f9fb955104f79bb8944f990e18184ba687f17198c4c53d37e' 
  AND token = 'OfcUS4t0oJ3pq5aq4LViYKQ+z4dJu31bySBbpifW0zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}