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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a43b892280857077e76fdb15ff5e0345c6b834b3441f4e5e6f5084aabfb2f2c' 
  AND token = 'Dl9N4t7gk/0PwzuIG/2QaaI8frsYTg2mmA5twekH10U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}