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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d4fa3a303782d0235ae31a1aba790006582b1751ce232d7ae8e73c96ceef14b' 
  AND token = 'DrDRapxNueu0i9FGCPf9nTHpWm8hNxYU2zNGWVuvlm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}