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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4248bd6aa499e32043a8b912069de6a8a000eed466476897fdb2fd3a4f26f44c' 
  AND token = '5dzWZLfS+FGbvc1eTNMIwM5PeSzvt35G/RhD2Dq33NM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}