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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf8a58687a0cd42655e8cfa6adc0bc23a6b5ee91dd80e63253ed0ce345ede794' 
  AND token = 'cM6//Oj3Zw3DJAgZNb65xjdHF8d7LSat4362OM0H+aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}