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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '352f4fb3107bd4abc7c0e9c9b8d26b792df3658541f4d4601968ce33846e220a' 
  AND token = '2jnmt4XmezkDG3Xd1KjZnM4ksmrblkdDtZoDQRqGf5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}