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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372a7c9d3d0d50987f3a744bf976e349d378ad3273b86d511c318832a7c1249e' 
  AND token = 'OU4h4J46uPudmbP7KRfDle99n4vL7KmnUN4EaEnFKAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}