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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5ba49538f9c5710a2a98e23d206a682a77ebc6c66435c551c9fee5e5463d2ec' 
  AND token = 'r5/VFqohSuIk2O6LDrpmMK31FKWFtE2mUjc4Sihh9sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}